Founded on 5 June 1224 by Holy Roman Emperor Frederick II (King of Sicily) via imperial charter, the University of Naples Federico II (Università degli Studi di Napoli Federico II) is recognized as the world's oldest state, public, and non-sectarian higher education institution in continuous operation. Celebrating its historic 800th anniversary (1224–2024), UNINA stands as the flagship research and academic university of Southern Italy and one of the largest comprehensive university systems in Europe, educating over 80,000 students across 26 academic departments and 4 major specialized schools: the Polytechnic & Basic Sciences School, the School of Medicine & Surgery, the School of Human & Social Sciences, and the School of Agriculture & Veterinary Medicine. UNINA's illustrious alumni and historical figures include Saint Thomas Aquinas, Giordano Bruno, Giambattista Vico, Italian Presidents Enrico De Nicola and Giorgio Napolitano, and modern European scientific pioneers. UNINA is an international research powerhouse hosting the renowned European Apple Developer Academy at San Giovanni a Teduccio, the Cisco Digital Transformation Lab, and the Quantum Information Hub. An anchor institution of the Aurora European University Alliance, UNINA offers more than 210 accredited undergraduate, single-cycle, master's, and doctoral programs, with over 35 programs delivered entirely in English.

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